Thursday Night Football: Lions vs. Bills – Week 2 Preview & How to Watch

Alright, football fans, the NFL’s Thursday night slot is back for Week 2 and it’s shaping up to be a solid early‑season showdown. The Detroit Lions, who already opened the season with a win, are packing up and heading to Highmark Stadium in Orchard Park, New York, to square off against the Buffalo Bills, also sitting at 1‑0.

The game is slated to kick off at 8:15 p.m. Eastern Time on Thursday, September 17. That means you’ll have a little extra time after the day’s usual grind to settle in, grab a snack, and get ready for some late‑night football drama.

When it comes to actually watching the matchup, you’ve got a few routes. For most viewers, the broadcast will be on ABC – the national feed – but if you’re in the Lions’ or Bills’ home markets, the game will also air on the local FOX affiliates (WJBK‑TV channel 2 in Detroit and WKBW‑TV channel 7 in Buffalo). So, depending on where you live, you might find it on either network.

If you’re more of a streaming‑only kind of person, Amazon Prime Video is the official home of Thursday Night Football for the fifth straight season. New Prime members can even snag a 30‑day free trial to catch the game live. In addition, the NFL’s own streaming service, NFL+, will carry the broadcast, giving you yet another way to tune in from a phone, tablet, or computer.

And for those who love the familiar voices that make the game feel like a weekly ritual, Al Michaels will be handling the play‑by‑play duties. His signature call‑outs should add that extra layer of excitement as the Lions try to stay perfect against a Bills team that’s already shown it can hang with anyone.

Bottom line: mark your calendars, set a reminder for 8:15 p.m. ET on September 17, and decide whether you’ll watch on ABC/FOX, stream via Prime Video, or fire up NFL+. Either way, you won’t want to miss this early‑season clash of two unbeaten clubs.