The 'Ketamine Queen' Pleads Guilty: A Pivotal Turn in Matthew Perry's Tragic Death Investigation
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- September 04, 2025
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In a significant development that brings new focus to the tragic passing of beloved actor Matthew Perry, Lisette Lee, notoriously known as the 'Ketamine Queen,' has pleaded guilty to an unspecified charge. This plea is directly connected to the ongoing investigation into the circumstances surrounding the 'Friends' star's death, which was ruled an accident due to the acute effects of ketamine.
Lee, whose past includes a high-profile conviction for drug trafficking, entered her plea in federal court, though the specific charge remains sealed from public view.
Her involvement adds a dramatic layer to the extensive probe launched by federal and local authorities to determine the source of the ketamine found in Perry's system at the time of his death in October 2023.
Matthew Perry, cherished by millions for his iconic portrayal of Chandler Bing, was found unresponsive in his Los Angeles home.
The Los Angeles County Medical Examiner's Office confirmed that his passing was a result of 'acute effects of ketamine' compounded by drowning, coronary artery disease, and the effects of buprenorphine. The report indicated that the ketamine levels in his blood were consistent with general anesthesia, far exceeding those used therapeutically, raising immediate questions about how the substance was acquired.
The joint investigation, spearheaded by the Drug Enforcement Administration (DEA) and the Los Angeles Police Department (LAPD), has meticulously traced leads to identify the individuals who supplied Perry with the fatal dose.
Lisette Lee's plea marks the most substantial public development in this complex and sensitive case, suggesting a breakthrough in understanding the supply chain.
Lee's history as the 'Ketamine Queen' stems from a 2010 federal conviction for operating a drug trafficking ring that smuggled hundreds of pounds of marijuana from Los Angeles to Ohio using private jets.
She served time for that offense, cementing her notorious reputation long before she became linked to the Perry investigation.
Her sentencing is currently scheduled for August 1, where the full implications of her plea and the potential penalties she faces – which could range from 15 years to life in prison – will be revealed.
This development brings the investigation closer to potentially unveiling the full truth behind the circumstances that led to the untimely death of a Hollywood legend, leaving fans and the public awaiting further answers.
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