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Record‑Setting Cyclospora Outbreak: What You Need to Know

Northwestern experts share practical advice for staying safe while enjoying fresh produce

A massive Cyclospora outbreak linked to shredded lettuce has sparked the biggest recorded case count in U.S. history. Dietitian Bethany Doerfler and gastroenterologist Stephen Chang explain the symptoms, who’s most at risk, and how simple cooking tweaks can keep your meals both healthy and safe.

Across at least five U.S. states, a wave of gastrointestinal illness caused by the single‑cell parasite Cyclospora has surged to unprecedented levels. Over 1,600 confirmed cases have been traced back to shredded iceberg lettuce served at a national fast‑food chain, prompting a massive recall of lettuce sourced from central Mexico. While officials are still probing unrelated spikes in other states, the situation has left many shoppers wondering if it’s time to overhaul their diets.

To cut through the headlines, Northwestern Now sat down with two campus experts: Bethany Doerfler, senior clinical research dietitian at Northwestern Medicine’s Digestive Health Institute, and Dr. Stephen Chang, assistant professor of gastroenterology at the Feinberg School of Medicine. Their goal? Give everyday readers clear, doable steps to stay healthy without giving up the vegetables they love.

What’s the single most effective habit? Doerfler says the answer is simple—apply heat. “Cooking higher‑risk greens and herbs to at least 160°F will kill Cyclospora,” she explains. Grilling, steaming, or turning leafy veggies into a soup are all practical ways to raise the temperature without sacrificing flavor.

But does cooking mean ditching fresh produce? Not at all. Doerfler stresses that “most fruits and vegetables have never been linked to an outbreak.” She recommends focusing on produce with thicker skins that can be peeled—think avocados, bananas, and melons. When you do use delicate greens, a quick toss on the grill or a brief steam can do the trick.

Doerfler also shares a personal habit: “We’ve been hitting the farmers market more than ever, picking up local greens instead of pre‑bagged lettuce, and cooking them whenever the recipe allows.” The message is clear—supporting local farms and cooking at home can lower risk while still delivering the nutrients you need.

Understanding the illness itself helps put the risk in perspective. Dr. Chang notes that Cyclospora’s symptoms—abdominal cramping, watery diarrhea, loss of appetite, occasional nausea or low‑grade fever—look a lot like any other stomach bug. “What sets it apart is the length of illness,” he says. “Symptoms can linger for weeks, sometimes months, before a proper diagnosis is made.”

In terms of severity, Chang adds that the parasite isn’t inherently more dangerous than bacterial or viral infections, but it can be tougher on certain groups. “Children, older adults, and anyone with a weakened immune system are most likely to experience severe dehydration or prolonged discomfort,” he warns.

When patients call in worried about a recent bout of diarrhea, the doctors remind them of the parasite’s incubation period: seven to ten days after exposure. “That timing helps us separate Cyclospora from more common causes like food‑borne bacteria that act faster,” Chang explains.

If diarrhea persists for more than a few days—especially with fever or signs of dehydration—Seek medical care, says Chang. Diagnosis typically involves a stool test specifically designed to detect Cyclospora oocysts. Prompt treatment with a short course of trimethoprim‑sulfamethoxazole can clear the infection quickly.

Bottom line: You don’t have to give up salads or fresh fruit. Heat your higher‑risk greens, choose produce you can peel, and stay alert for prolonged gastrointestinal symptoms. By making a few mindful tweaks, you can keep enjoying a plant‑rich diet while steering clear of this record‑setting outbreak.

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