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QB Conundrum: Brock Purdy Questionable for Critical 49ers-Cardinals Showdown

  • Nishadil
  • September 20, 2025
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QB Conundrum: Brock Purdy Questionable for Critical 49ers-Cardinals Showdown

The NFL landscape often shifts with a single word – 'questionable.' For the San Francisco 49ers, that word now hangs heavily over their star quarterback, Brock Purdy, as they brace for a critical Week 3 showdown against the Arizona Cardinals. Purdy, whose meteoric rise captivated the league, is officially listed as questionable for Sunday’s pivotal NFC West clash due to a nagging shoulder injury sustained earlier in the week.

Head coach Kyle Shanahan, usually a master of calm, has been a model of cautious optimism regarding Purdy's recovery.

However, the reality of a 'questionable' tag means the team is preparing for all contingencies. Should Purdy be unable to take the field, the 49ers will turn to either Trey Lance or Sam Darnold to steer the ship. Both quarterbacks have been diligently preparing, understanding the monumental task of filling Purdy’s shoes in a high-stakes divisional game.

The decision on who starts will undoubtedly be one of the most scrutinized of the young season.

But Purdy isn't the only 49er battling the injury bug. The prolific wide receiver Deebo Samuel is also listed as questionable with a rib injury, a concern that could significantly impact the team's explosive offensive scheme.

His absence, coupled with Purdy's potential sideline status, would force offensive coordinator Klint Kubiak to dig deep into the playbook and rely on other playmakers. On the defensive side, cornerback Charvarius Ward is questionable with a groin issue, which could challenge the secondary's coverage against a Cardinals offense that has shown flashes of brilliance.

Amidst these concerns, there's a beacon of positive news: defensive end Nick Bosa, the reigning Defensive Player of the Year, was a full participant in practice, indicating he's ready to bring his usual disruptive force to the line of scrimmage.

While Bosa's presence is a huge boost, the collective weight of the other injuries, particularly at the quarterback position, casts a long shadow over the 49ers' preparations. This isn't just another game; it's an NFC West slugfest with early-season bragging rights and playoff implications on the line.

The Arizona Cardinals, though perhaps flying under the radar, are no strangers to their own injury woes but will undoubtedly be looking to capitalize on any instability within the 49ers' ranks.

This matchup, already circled on calendars as a must-watch, has now gained an even higher level of intrigue. All eyes will be on Levi's Stadium as fans await the final word on Purdy's status, knowing that the outcome of this crucial divisional battle could hinge on who ultimately takes the snaps for San Francisco.

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