NFL Week 4: The Injury Report That Could Redefine the Weekend!
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- September 23, 2025
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As Week 4 of the NFL season rapidly approaches, the gridiron is buzzing with anticipation, and for many, a palpable sense of anxiety. The latest injury reports are rolling in, and they paint a picture of uncertainty for several key players, promising to shake up both team strategies and countless fantasy football lineups.
The availability of these stars could dramatically swing outcomes, making this weekend's matchups even more compelling.
Perhaps the most significant question mark hovers over Las Vegas Raiders' electrifying wide receiver, Davante Adams. Nursing a shoulder injury, Adams has been officially listed as questionable.
His potential absence or limited participation would be a massive blow to the Raiders' aerial attack, forcing Derek Carr to find alternative targets and adjust their game plan against a formidable opponent. The Raiders' offensive identity often flows through Adams, and his status is paramount for their Week 4 prospects.
Indianapolis Colts' workhorse running back, Jonathan Taylor, remains sidelined with an ankle injury, officially ruled out for Week 4.
This continues to be a storyline watched closely by Colts fans and fantasy managers alike. His absence means the Colts will continue to rely on their other backfield options, hoping to generate enough ground production to support their offense.
The Green Bay Packers are facing a double whammy at wide receiver.
Both Christian Watson and Aaron Jones are listed as questionable with hamstring injuries. The potential loss of two such dynamic offensive weapons would severely cripple the Packers' offensive diversity and force Jordan Love to operate with a significantly depleted arsenal. Their status will undoubtedly dictate much of Green Bay's offensive strategy.
From the AFC West, the Los Angeles Chargers will once again be without their versatile running back, Austin Ekeler, who is out with an ankle injury.
Ekeler is a cornerstone of the Chargers' offense, a dual-threat menace in both the run and pass game. His continued absence puts immense pressure on backup running backs and quarterback Justin Herbert to elevate their game.
Meanwhile, the Carolina Panthers are monitoring the status of running back Miles Sanders, listed as questionable with a groin issue.
Sanders' ability to contribute would be vital for the Panthers' ground game as they navigate a challenging Week 4 opponent. The New Orleans Saints will also be without their powerful running back, Jamal Williams, who is out with a hamstring injury, further testing their backfield depth.
Other notable players on the Week 4 injury report include New York Giants' superstar running back Saquon Barkley, who is out with an ankle injury, leaving a gaping hole in their offense.
The Saints' starting quarterback, Derek Carr, is questionable with a shoulder injury, a situation that could have massive implications for their offensive production if he's unable to play or is limited. Miami Dolphins' wide receiver Jaylen Waddle is questionable with a concussion, an injury that always warrants careful consideration.
Buffalo Bills' receiver Gabe Davis (ankle), Cleveland Browns' receiver Amari Cooper (foot), Seattle Seahawks' running back Kenneth Walker III (calf), and Baltimore Ravens' running back Justice Hill (foot/toe) are also all listed as questionable, adding further layers of uncertainty to an already exciting NFL Sunday.
For teams and fantasy managers alike, staying glued to the final injury updates before kickoff will be crucial.
The outcome of several key matchups this weekend could very well hinge on which of these star players take the field, and in what capacity. Get ready for a thrilling, and potentially unpredictable, Week 4!
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Disclaimer: This article was generated in part using artificial intelligence and may contain errors or omissions. The content is provided for informational purposes only and does not constitute professional advice. We makes no representations or warranties regarding its accuracy, completeness, or reliability. Readers are advised to verify the information independently before relying on