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Cardinals' Week 1 Showdown: Who's In, Who's Out for the Season Opener!

  • Nishadil
  • September 08, 2025
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Cardinals' Week 1 Showdown: Who's In, Who's Out for the Season Opener!

As the roar of the crowd signals the start of a new NFL season, the Arizona Cardinals have officially released their inactive list for the highly anticipated Week 1 clash. Fans and analysts alike have been eagerly awaiting this announcement, as it sets the stage for who will be leading the charge and who will be watching from the sidelines.

Leading the list of notable absences is veteran Left Tackle D.J.

Humphries, who will miss the season opener due to a lingering knee injury. This absence is a significant blow to the offensive line, putting immediate pressure on the team's depth. Stepping into the crucial role will be rookie sensation Paris Johnson Jr., making his NFL debut at the pivotal left tackle position.

All eyes will be on Johnson to see how he handles the challenge of protecting the quarterback against an aggressive pass rush.

Joining Humphries on the inactive list due to injury is Cornerback Garrett Williams, whose undisclosed ailment will keep him out of commission. This further tests the Cardinals' secondary, requiring other defensive backs to step up and fill the void against a potent passing attack.

In terms of healthy scratches, the Cardinals have opted to hold out Offensive Lineman Hjalte Froholdt and Defensive Lineman Dante Stills.

These decisions indicate the coaching staff's confidence in the players ahead of them on the depth chart, and perhaps a strategic move to rotate personnel based on the opponent. Third-string Quarterback Clayton Tune is also among the inactives, a standard practice for many NFL teams unless an emergency situation dictates otherwise.

The declaration of these inactives means that every player on the active 53-man roster, excluding the aforementioned individuals, will be available to play.

This includes key starters and vital role players who will be instrumental in the Cardinals' quest for an opening week victory. The team's resilience and depth will be tested from the very first snap of the 2025 season, making this Week 1 matchup an even more compelling watch for the Red Sea faithful.

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