UCLA Researcher Olivia Justynski Secures Major Grant to Revolutionize Liver Cancer Treatment

In a significant boost for the fight against one of the most challenging cancers, UCLA postdoctoral researcher Olivia Justynski has been awarded a prestigious two-year grant from the American Cancer Society (ACS). This pivotal funding will propel her innovative research into developing new and much-needed treatments for liver cancer, a disease with devastating prognoses for many.

Justynski, working diligently in Dr.

O. Joe Hines' lab at the David Geffen School of Medicine, is at the forefront of deciphering the complex mechanisms behind liver regeneration and how these processes can tragically go awry, paving the way for cancer. Her work focuses specifically on understanding the intricate dialogue between different cell types within the liver – particularly macrophages, which are critical immune cells, and hepatocytes, the primary liver cells.

She's exploring how their communication influences the liver's ability to repair itself after injury.

A key player in Justynski's research is the protein "Yes-associated protein," or YAP. This protein is a central regulator in both normal liver regeneration and the progression of liver cancer.

By meticulously investigating YAP's role and its interactions with various cellular pathways, Justynski aims to uncover novel therapeutic targets that could effectively block the development and advancement of liver cancer, offering a beacon of hope for patients worldwide.

The American Cancer Society grant is not merely financial support; it's a profound recognition of Justynski's promising work and her potential to make a substantial impact on oncology.

This competitive award provides her with the essential resources and autonomy to dive deeper into her hypothesis-driven research, allowing for critical experiments and analysis that would otherwise be difficult to pursue.

Liver cancer remains a formidable challenge, often diagnosed at advanced stages when treatment options are limited.

The insights gained from Justynski's research could fundamentally change how we approach this disease, leading to more effective therapies and ultimately, saving lives. Her dedication embodies UCLA's commitment to pioneering medical breakthroughs and delivering hope through cutting-edge science.