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Ovid Therapeutics Soars: A Game-Changing Deal with Takeda Propels Stock by 18%

  • Nishadil
  • October 04, 2025
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  • 1 minutes read
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Ovid Therapeutics Soars: A Game-Changing Deal with Takeda Propels Stock by 18%

Ovid Therapeutics (NASDAQ: OVID) shareholders woke up to exhilarating news as the company's stock experienced a dramatic 18% surge in pre-market trading. The catalyst for this significant rally? A groundbreaking licensing agreement with pharmaceutical giant Takeda Pharmaceutical Company (NYSE: TAK) that promises to redefine Ovid’s financial landscape and strategic focus.

The deal centers around TAK-935/OV935, also known as soticlestat, a promising gene therapy program in Ovid’s pipeline.

This innovative treatment is specifically designed to address developmental and epileptic encephalopathies (DEEs), a group of severe and often debilitating forms of epilepsy. Crucially, soticlestat targets conditions like Dravet syndrome and Lennox-Gastaut syndrome (LGS), which currently have limited effective treatment options and represent areas of significant unmet medical need.

Under the terms of this highly favorable agreement, Takeda will take the reins of soticlestat's global development and commercialization.

This means Ovid Therapeutics will no longer be responsible for funding the clinical advancement of the therapy, effectively de-risking a major asset. In return, Takeda has committed an impressive $195 million upfront payment to Ovid, providing an immediate and substantial injection of capital.

The financial upside for Ovid doesn't stop there.

The agreement also includes potential future payments totaling up to $850 million in development, regulatory, and commercial milestones. Beyond these milestones, Ovid is also set to receive tiered royalties on net sales, ensuring a long-term revenue stream should soticlestat successfully reach the market and gain traction.

This strategic move is a monumental win for Ovid Therapeutics.

For a company whose stock has experienced considerable volatility—ranging from a 52-week low of $2.27 to a high of $8.89—this deal provides a much-needed boost in confidence and financial stability. It allows Ovid to bolster its balance sheet significantly while simultaneously freeing up resources to focus on other promising programs within its development pipeline.

By offloading the substantial costs and risks associated with late-stage clinical trials and commercialization for soticlestat, Ovid Therapeutics has executed a masterstroke.

The partnership with Takeda, a global leader in pharmaceuticals, not only validates the potential of soticlestat but also positions Ovid for sustained growth and innovation, much to the delight of its investors.

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